Why Do We Eat? A Neurobiological Perspective. Part V

In previous posts, I explained that food intake is determined by a variety of factors that are detected by the brain, and integrated by circuits in the mesolimbic system to determine the overall motivation to eat.  These factors include 'homeostatic factors' that reflect a true energy need by the body, and 'non-homeostatic factors' that are independent of the body's energy needs (e.g. palatability, habit, and the social environment).

In this post, we'll explore the hedonic system, which governs pleasure.  This includes the pleasure associated with food, called palatability.  The palatability of food is one of the factors that determines food intake.

The Hedonic System

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Why Do We Eat? A Neurobiological Perspective. Part IV

In this post, I'll follow up on the last post with a discussion two more important factors that can affect energy homeostasis and therefore our food intake and propensity to gain fat: age and menopause.

Age

Although it often isn't the case in non-industrial cultures, in affluent nations most people gain fat with age.  This fat gain continues until old age, when many people once again lose fat.  This is probably related to a number of factors, three of which I'll discuss.  The first is that we tend to become less physically active with age.  The second, related factor is that we lose lean mass with age, and so energy expenditure declines.

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Why Do We Eat? A Neurobiological Perspective. Part II

In the last post, I explained that eating behavior is determined by a variety of factors, including hunger and a number of others that I'll gradually explore as we make our way through the series.  These factors are recognized by specialized brain 'modules' and forwarded to a central action selection system in the mesolimbic area (the reward system), which determines if they are collectively sufficient cause for action.  If so, they're forwarded to brain systems that directly drive the physical movements involved in seeking and consuming food (motor systems).

The term 'homeostasis' is important in biology.  Homeostasis is a process that attempts to keep a particular factor within a certain stable range.  The thermostat in your house is an example of a homeostatic system.  It reacts to upward or downward changes in a manner that keeps temperature in a comfortable range.  The human body also contains a thermostat that keeps internal temperature close to 98.6 F.  Many things are homeostatically regulated by the body, and one of them is energy status (how much energy the body has available for use).  Homeostasis of large-scale processes in the body is typically regulated by the brain.

We can divide the factors that determine feeding behavior into two categories, homeostatic and non-homeostatic.  Homeostatic eating is when food intake is driven by a true energy need, as perceived by the brain.  For the most part, this is eating in response to hunger.  Non-homeostatic eating is when food intake is driven by factors other than energy need, such as palatability, habitual meal time, and food cues (e.g. you just walked by a vending machine full of Flamin' Hot Cheetos).

We can divide energy homeostasis into two sub-categories: 1) the system that regulates short-term, meal-to-meal calorie intake, and 2) the system that regulates fat mass, the long-term energy reserve of the human body.  In this post, I'll give an overview of the process that regulates energy homeostasis on a short-term, meal-to-meal basis.

The Satiety System (Short-Term Energy Homeostasis)


The stomach of an adult human has a capacity of 2-4 liters.  In practice, people rarely eat that volume of food.  In fact, most of us feel completely stuffed long before we've reached full stomach capacity.  Why?

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Why Do We Eat? A Neurobiological Perspective. Part I

As with all voluntary movements, eating food is an expression of activity in the brain.  The brain integrates various inputs from around the body, and outside the body, and decides whether or not to execute the goal-directed behaviors of food seeking and consumption.  Research has uncovered a lot about how this process works, and in this series I'll give a simplified overview of what scientists have learned about how, and why, the brain decides to eat.

The Gatekeeper of Voluntary Behaviors

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Announcing the Ideal Weight Program

I often receive requests from people asking for my overall perspective on fat loss and health.  I share my opinions here, but they're scattered throughout hundreds of posts, there's a lot I haven't had a chance to write about, and I rarely give practical recommendations.  However, I knew I'd eventually put everything together into a cohesive fat loss program-- it was only a matter of finding the right opportunity.

That opportunity presented itself in 2011 when I met Dan Pardi, a researcher whose work focuses on sleep and food intake, and the CEO of a company called Dan's Plan.  I was immediately impressed by Dan because he stood out as someone with a high level of expertise in sleep and physical activity, as well as someone who has successfully lost a substantial amount of fat and kept it off for several years.


Dan and his team had developed a set of unique and engaging tools for tracking weight, sleep, and physical activity to help people maintain daily mindfulness over the simple fundamentals of health.  These tools are 100 percent free and incredibly easy to use, particularly if you sync them with an electronic scale and step counter.  When synced with these devices, the Dan's Plan website automatically uploads and displays your weight, sleep, and physical activity score, as well as integrating them all into a single user-friendly Health Zone Score that lets you know your overall performance at a glance.  Even if you have no interest in fat loss, I highly recommend using the free tracking tools on the Dan's Plan site-- I do.

In early 2012, Dan approached me about creating a fat loss program for Dan's Plan that incorporates their unique tracking tools.  This struck me as an excellent opportunity to create a diet and lifestyle program that combines sound science with exciting new technology.  Dan and I both brought science to the table, and Dan also brought the perspective gained from working with others to help them lose fat, as well as his own successful fat loss experience.  Dan and I have been working hard on this project, and we're finally ready to launch.

I'm happy to announce the Ideal Weight Program, an effective new system for fat loss and maintenance.

What is the Ideal Weight Program?

The Ideal Weight Program is a unique system for fat loss and maintenance that draws from the latest science on diet, physical activity, sleep, and behavior modification, and pairs it with engaging tools that help you define your goals and meet them.  It keeps you consistently focused on the everyday factors that really matter for fat loss, and gives you the skills you need to make sustainable diet and lifestyle changes.  Based on your own goals and priorities, you can choose one of two diet strategies for the initial fat loss phase:
  • The Fat Loss and Sustainable Health (FLASH) diet, an intensive high-protein diet for rapid fat loss.
  • The Simple Food Diet, a more flexible diet based on whole, natural foods specifically selected for fat loss.  One important goal of this diet is to teach healthy cooking skills, using recipes and tips provided.
These diets are designed to naturally promote a lower calorie intake and fat loss, without requiring calorie counting.  The Ideal Weight Program also includes important physical activity and sleep components, and explains why these are so critical for fat loss and health.  Dan and I discussed some of the principles underlying the Ideal Weight Program on Chris Kresser's podcast recently.

Here's what you get when you sign up:
  • Detailed documents that walk you through the program
  • Weight, sleep, and physical activity tracking tools tailored for fat loss
  • Simple recipes and cooking tips that work with almost anything in your fridge
  • Videos that explain the key concepts behind fat loss and maintenance
  • An e-book explaining the scientific rationale behind the program
Signing up for the Ideal Weight Program gives you lifetime access to everything.  We've discounted the initial price, because we want to hear your feedback so that we can continue to improve the program over time.  If you follow the link below, first you'll be prompted to sign up for a basic Dan's Plan account, and once you have your account set up, you'll be able to purchase the Ideal Weight Program:

Ideal Weight Program



Financial disclosure: I will receive a portion of the revenue from the sale of the Ideal Weight Program.  I do not receive revenue from the sale of other products associated with Dan's Plan or the Ideal Weight Program (such as the Fitbit, cooking tools, and other programs).

...over and done

Fresh winds are blowing - a distant, subtle fragrance in the air - flux and evolution - all good. No more to add this week other than the events, exhibition, funding, commission and training offered below.


A reminder that if you want to come to the Networking Event at MMU on Thursday 7th Feb that has input of guests from Italy and Turkey and a focus on the arts in relation to recovery, you have to register at artsforhealth@mmu.ac.uk and details of the venue and other information, will be sent early next week.

The following short film is another eye-flickering response to some of the conversations I’ve had with people about re-imagining this arts/health field in relation to the here and now. (see previous blogs) Please don’t click on the film if you react badly to flashing images. 

Birth Rites Collection
The shortlisted entries for the Birth Rites Collection’s bi-annual art prize will be showcased at the University of Salford’s MediaCityUK campus on Saturday 2 February. The Collection was established by Helen Knowles, an artist and curator who aims to encourage a wider debate about the politics and practice of childbirth through the use of art. It was inspired by Helen’s contrasting experiences of giving birth to her first child in a hospital by cesarean and her second born at home. The exhibition at MediaCityUK will feature the drawings, films, photographs and sculptures of 15 shortlisted artists from all over the world. The prize is a month at artistic retreat The Trelex Residency in Geneva (including the cost of flights and a stipend) plus a place in the Birth Rites Collection.


The short-listed artworks include Emma Lazenby’s BAFTA-winning short animation about a midwife, Mother of Many (see below), photographs of women's faces at the moment of birth by Dominika Dzikowska, "illegitimate hallucinations", by Giorgio Sadotti and YouTube videos of childbirth flanked by photographs of people watching them by Claire Lawrie. 

The winner of the competition will be announced at the event by curator Helen Knowles and fellow judge Hermione Wiltshire, an artist and senior lecturer in photography at the Royal College of Art.

Helen said: “The taboo and under-represented subject of birth has been shown to be of great importance as a topic for artists to explore. We have had a great number of excellent submissions to the competition and this show presents a broad spectrum of works which were found to be the most poignant. Imagery on this fundamental life-process is a great way for people to get to grips with what it means to give birth today." 

The Birth Rites Collection is housed at the University of Salford in the midwifery department and the Royal College of Gynaecologists and Obstetricians in London. Birth Rites, Saturday 2 February, 11.00am – 5.00pm, The Egg, University of Salford, MediaCityUK. Prize to be awarded at 2pm.


Music in Healthcare Settings Training
We are proud to announce details of our next Music in Healthcare Settings training programme for musicians, to take place on 11, 12, 15, 16 and 17 April 2013 in Derby, UK. More details and an application form are available from our website here: Places are limited - applicants are advised to send an application asap. http://www.opusmusic.org/?p=437 

Tesco Charity Trust Community Awards (UK)
Deadline: Sun 30 Jun 2013
The Tesco Charity Trust Community Awards Scheme has announced that its funding programme for children’s education and children’s welfare will re-open for applications on 1 December 2012. The scheme awards one-off donations of between £500 and £4,000 to registered charities, schools and not-for-profit organisations. The funding they give can go towards providing practical benefits, such as equipment and resources for projects that directly benefit children living in the local communities around Tesco stores in the UK.

Applications should be made between 1 December – 30 January and 1 May – 30 June. The deadline for applications is Wednesday 30 January and Sunday 30 June 2013. To find out more about the Awards and how to apply, please click on the carrier bag below. 



Greggs Foundation Grants
Deadline: Mon 18 Feb 2013
Local not-for-profit organisations can apply for grants of up to £2,000 through the Greggs Foundation regional grants Programme. The programme is administered by committees of volunteers from Greggs shops, bakeries and offices who are based in England, Scotland and Wales.  They use their knowledge of the local area to make small grants to local organisations, in particular those that make a difference to people in need in the heart of Greggs’ local communities. The Greggs Foundation prioritises local organisations that help people in need in their local area, with previous funding helping towards trips, activities and equipment. Additionally the Foundation prioritises the following people:

  • Voluntary carers
  • People with disabilities
  • Homeless people
  • Older people
The deadline for applications is Monday 18 February 2013. Read more by clicking on the pies. 



Grants to Help New, Innovative Visual Arts Projects (UK)
The Elephant Trust has announced that the next deadline for applications is the 15th April 2013.  The Trust offers grants to artists and for new, innovative visual arts projects based in the UK. The Trust's aim is to make it possible for artists and those presenting their work to undertake and complete projects when confronted by lack of funds. The Trust supports projects that develop and improve the knowledge, understanding and appreciation of the fine arts. Priority is now being given to artists and small organisations and galleries who should submit well argued, imaginative proposals for making or producing new work or exhibitions. Arts Festivals are not supported. The Trust normally awards grants of up to £2,000, but larger grants may be considered. Read more at: 

Public Art Commission: Liverpool & Sefton Health Partnership Ltd in co-operation with Mersey Care NHS Trust
Liverpool & Sefton Health Partnership Ltd (LSHP) Art Commission
(in co-operation with Mersey Care NHS Trust)
LSHP is calling for applications from experienced and suitably qualified artists/artist teams for the commission of a high impact piece of art at the entrance of the mental health facility which provides a message of hope, optimism and wellbeing for Mersey Care NHS Trust’s service users, staff and neighbours. 

The local community and service users will be at the heart of this project and the selected artist/artist teams must demonstrate how they will work with the community and service users to develop a sense of ownership of the building and its surrounds. Therefore the artist/artist team must also outline the approach they will take to engage and work with the local community and mental health service users. LSHP will expect applicants to showcase previous commissions where they have experience of successful public engagement.
Applicants are requested to read the full contents of the  Artist Brief and Application Process document carefully as it contains important information about the application process and terms of reference. Deadline: 12.00noon, Friday 22rd March 2013. full details by clicking on the Olympia Theatre below.




Is Photography inherently racist?
Adam Broomberg & Oliver Chanarin  
To Photograph the Details of a Dark Horse in Low Light 
The Goodman Gallery in Johannesburg is presenting two new related bodies of work by Adam Broomberg and Oliver Chanarin. The following text is taken from the gallery website. In 1970, Caroline Hunter, a young chemist working for the Polaroid Corporation, stumbled upon evidence that her multinational employees were indirectly supporting apartheid. With the collusion of local distributors Frank & Hirsch, Polaroid was able to provide the ID-2 camera system to the South African state, to efficiently produce images for the infamous passbooks. The camera included a boost button designed to increase the flash when photographing subjects with dark skin. Alongside her partner Ken Williams they formed the Polaroid Workers Revolutionary Movement, and campaigned for a boycott. By 1977, Polaroid finally did withdraw from South Africa, and the international divestment movement – which eventually crippled apartheid – was on its way. The radical notion that prejudice might be inherent in the medium of photography itself is interrogated by the artists Broomberg and Chanarin in this presentation of new works produced on salvaged polaroid ID-2 systems.


Early colour film was known to be predicated on white skin and in 1977 when Jean-Luc Godard was invited on an assignment to Mozambique, he famously refused to use Kodak film on the grounds that the film stock was inherently ‘racist’. The title of Broomberg and Chanarin’s exhibition was originally the coded phrase used by Kodak to describe the capabilities of a new film stock developed in the early ’80s to address the inability of their earlier films to accurately render dark skin. In response to a commission to ‘document’ Gabon, Broomberg and Chanarin recently made two trips to the country to photograph a series of rare Bwiti initiation rituals, using only Kodak film stock that had expired in the late 1970s. Working with outdated chemical processes they succeeded in salvaging just a single frame from the many expired colour rolls they exposed during their visit. In this wide-ranging meditation on the relationship between photography and race, the artists continue to scrutinise the photographic medium, leading viewers through a convoluted history lesson; a combination of found images, rescued artifacts and unstable new photographic works.


Comment Published in Nature

I recently read an opinion piece by Gary Taubes in the scientific journal Nature, titled "Treat Obesity as Physiology, not Physics", in which he promoted NuSI and repeated the statement that obesity research is a "house of cards" because it focuses on calories in/out, at the expense of studying the "hormonal regulatory disorders" underlying obesity (1).  I wrote a letter to the editor in response to Taubes's commentary, which has been published in Nature (2).

I'm used to seeing these kinds of claims in the popular press at this point, but to see it published in a scientific journal is galling (even if it's in the opinion section).  This is the equivalent of a person who has never held an ax telling a group of lumberjacks they need to focus on cutting trees.  It's part of a disturbing trend of popular writers in the low-carb and Paleo world attacking researchers, and even entire fields of research, they have little understanding of.  Of course this only applies to a minority of the community, but this argumentation style smells of desperation and reflects poorly on the community as a whole.

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Dogs Eating Carbs

Five years ago, I had an interesting conversation with a veterinarian friend about dog food.  We were talking about diabetes in one of the dogs she was treating, and I remarked "that's what happens when you feed a carnivore carbohydrate".  She gave me a funny look.  At the time, I was seeing the world through the low-carb lens, and I remember thinking how bizarre it was that she didn't yield to my impeccable logic.  As they say, live and learn.

The journal Nature published a fascinating paper on the evolution of the domestic dog today (1).  Researchers compared the genome of wolves and domestic dogs to see what genetic changes accompanied domestication.

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...?




This week I took on the role of chair of the National Alliance for Arts, Health & Wellbeing and it promises to be an interesting period of development in the field. More of that very soon. Not entirely unconnected, I would like to talk to anyone who has had experience of mentoring in this arts and health world. I’m particularly interested in exploring reverse mentoring, whereby people who are slightly (hmmm) ‘long-in the-tooth’ like me, might benefit from a younger and dynamic arts/health person, perhaps someone who didn’t knowingly start out on this path, but finds either their health or arts journey has led them to thinking about this work - or perhaps someone whose start in life hasn’t been ‘conventional’. So, a two-way street in mentoring to benefit both partners. Get in touch if you’ve ideas on this.

People laughing their heads off at a Networking Event 
The first networking event with a focus on arts and recovery is set for Thursday 7th February and details of timings will be sent out to those of you who have registered a few days before. As though that’s not enough for February, I’ll be holding another session on Thursday 28th February between 6:00 and 8:00PM! I’m exploring how we define this arts and health thing that we do, and talking with friends and colleagues in Lithuania, we’ve been unpicking a very early John Angus Arts and Health Framework that he produced for the Health Development Agency back in 2002. It’s got me started exploring how we can better tell our story in words and ‘pictures’... What on earth do I mean? Well, how are we evolving? Is it just the same old synergies, divisions and silos, or are we thinking differently? SO - I’ll have done some preparatory work for the session, but it will be an interactive evening where we all contribute to visualising where we feel the field is at this ever-evolving moment in time. The little film at the top of the page, is a starting point for me. To take part in this event, you’ll need to register here artsforhealth@mmu.ac.uk 

Did you know that Manchester boasts at least 153 languages, making it one of the worlds most diverse places? According to University of Manchester linguist, Professor Yaron Matras the list could get even higher! He comments that “Manchester’s language diversity is higher than many countries in the world. It is very likely to be top of the list in Europe, certainly when compared to other cities of its size, perhaps only outflanked by London and Paris. We do know that around two thirds of Mancunian schoolchildren are bilingual  - a huge figure which indicates just how precious its linguistic culture is.” To find out more click on the animals below.


Celebrate Chinese New Year
SNAKE MUSIC at the CHINESE ARTS CENTRE
Thursday 7th February 8pm 
On the evening of the first networking event you can follow all the excitement and celebrate the Year of the Snake with a fusion of Chinese music, jazz, beats and inspiring tunes featuring the amazing Yin Ng. This renowned composer, arranger and performer was the “musician of the Year” in Hong Kong in 2012. Yin has worked with More Music for over 6 years which included working on the inspiring LONG WALK project in Hong Kong in 2009. This piece was created by Artistic Director of More Music, Pete Moser, as a response to the Morecambe Bay tragedy of 2004 and was made and performed in Morecambe, Gateshead, Liverpool and Hong Kong. More details about this event can be found by clicking on this Ai Weiwei snake made in response to the 2008 Sichuan earthquake that left nearly 90,000 people dead or missing. Many of the victims were students who died when their poorly constructed schools collapsed on them.  Called "Snake Ceiling", it is made of hundreds of backpacks latched together in the shape of a snake. These are meant to represent children's backpacks left behind after the earthquake. Ai said he saw numerous piles of backpacks outside schools when he traveled to Sichuan following the disaster. 


Musical Spaces in Medical Places
A one-day training & workshop opportunity following our Music & Wellbeing agenda, in conjunction with the Royal Northern College of Music.
Published on: 10/01/2013 A fantastic Making Music training opportunity at the RNCM for musical groups who would like to take their music into hospitals or other medical places. Led by experts in this field, Ros Hawley and Mark Fisher, the day will equip you with new skills to enter this rewarding sector. Read more and register your interest by clicking on the sublime Musique et Sante musician, Dédé Saint-Prix.


Developing Supportive Design 
for People with Dementia 
There is growing awareness of the importance of the environment within health care. The King's Fund's Enhancing the Healing Environment (EHE) programme encourages and enables nurse-led teams to work in partnership with patients to improve the environment in which to deliver care. This publication seeks to provide practical, value-for-money examples to encourage and inspire staff and their organisations to provide an environment of care that better supports people with dementia. As well as case studies with before and after photographs from participating sites, Developing Supportive Design for People with Dementia includes information about the development and evaluation of the EHE assessment tool; overarching design principles for creating a more supportive environment for people with dementia; and a project directory detailing the artists and designers involved in each scheme along with costs involved. Click on the graphic below for more details.



TWO MAJOR CONTRACTS
Family Friendly Arts Campaign MA Contracts available, The Family Friendly arts campaign is inviting tenders for two major pieces of work:

The Big Venture Challenge (North West)
The Big Venture Challenge, a national competition seeking to find the 30 most ambitious social entrepreneurs in England, has announced that it is open for applications.  Big Venture Challenge is looking for people:
• With big ideas to transform disadvantaged communities across England
• Who have got what it takes to build credible ventures
• Who have the ambition to be scaled up fast.

To be eligible to apply applicants must be 16+, be founders of the venture, and be based in England. Those selected as one of the 30 Big Challenge Award Winners will participate in an intensive 12 month programme that is designed to help raise external investment (debt or equity) of between £50,000 to £250,000.  The Big Venture Challenge will run themed and regional cohorts every year in order to build deeper, more relevant strategic support networks around each cohort. In 2013 the themed cohort will be in Health and Social Care and the regional cohort will be in the North West of England.  The applications closing date is 9am on the 8th February 2013. Read more at: http://unltd.org.uk/bvc/entrepreneur

People's Postcode Trust Small Grants Programme 
(England, Scotland & Wales)
The People's Postcode Trust has announced the first funding round for the 2013 small grants programme is now open. Through its small grants programme, the People's Postcode Trust offers grants of between £500 and £10,000 to small organisations and community groups for projects lasting up to 6 months in the areas of:

  • Poverty Prevention
  • Advancement of Health
  • Community Development
  • Public Sports
  • Human Rights
  • Environmental Protection.
This funding round is open to organisations in Scotland, Wales and Northern England.  The closing date for applications is the 22nd February 2013. For further information on this and future funding rounds please click: http://www.postcodetrust.org.uk/



New Grants Programme for Gypsy Roma & Traveller Groups (UK)
The Travellers Aid Trust has announced the launch of a new grants programme for Gypsy Roma and Traveller groups.  Funded by the Esmée Fairbairn Foundation, the programme will make grants of between £5,000 and £20,000 to Gypsy Roma and Traveller groups to help skill up young people, improve literacy and work with offenders.  The Travellers Aid Trust expects to award between 7 and 10 grants a year over the next two years.
The closing date for the first round of applications is the 8th February 2013. Read more by clicking the image above.


...and a song to keep you bemused with slightly creepy tigers and rabbits cycling into an inky dark place...